Tuesday, October 14, 2014

Marijuana is legal under the 1938 amendments to the Pure Food and Drug Act of 1906, we do need to regulate it.

Marijuana is legal under the 1938 amendments to the Pure Food and Drug Act of 1906, which remains the standard for prescription and non-prescription drugs (making in the case of marijuana, the controlled substances act out of line and unconstitutional and infringement of the duties and obligations of the FDA)
http://en.wikipedia.org/wiki/Pure_Food_and_Drug_Act

"Goods found in violation of the law were subject to seizure and destruction at the expense of the manufacturer. That, combined with a legal requirement that all convictions be published (Notices of Judgment), proved to be important tools in the enforcement of the statute and had a deterrent effect upon would-be violators. "

http://www.fda.gov/AboutFDA/Transparency/Basics/ucm214416.htm
"The enactment of the 1938 Food, Drug, and Cosmetic Act tightened controls over drugs and food, included new consumer protection against unlawful cosmetics and medical devices, and enhanced the government’s ability to enforce the law. This law, as amended, is still in force today."
And of course, as we all know, the FDA has not made marijuana an FDA approved prescription in any state, mostly because it is available as a "dangerous" but legal drug, in the same wording as surrounds the alcohol industry.
We need better regulation  of these substances. The prohibition is ineffective and morally unjustifiable. 
http://www.thenewamerican.com/usnews/item/18383-house-votes-to-stop-feds-from-interfering-with-state-marijuana-laws
The house has already voted to end Department of Justice funding for marijuana prosecution.

The effect of potent unregulated or decriminalized marijuana and alcohol versus legalized and properly regulated marijuana and alcohol (with proper FDA regulations full brain blood-flow should be possible regardless of which substance is consumed, though it would appear to be quite low, .5% in the case of alcohol, over half a dozen strains of marijuana are already identified that are purported to be safe some that may even contain moderate amounts of THC):
https://www.youtube.com/watch?v=UjZgj_eH4x0

In addition, while the Controlled Substances Act of 1976 (the version in 1970 was still diagnostic in effect) gave federal agencies jurisdiction to act in the case of many drugs, including marijuana, this was in spite of a decriminalization law passed in 1973, still legally and enforced in the state of North Carolina. It was not out of error that the legislation in North Carolina passed this bill, they simply were regulating a dangerous industry concluding indemnifying research that showed alcohol and tobacco to be far worse than cannabis, legally according to the FDA regulations on the product and in keeping with importation laws from nations where it was legal to possess or produce (at the time 1/2 ounce in North Carolina, the substance was legal in many parts of the world notably the Netherlands and Morocco, where multiple brutal civil wars have been fought over the legalization of the product and the monarchy's succession). Under the same legal logic that made the emancipation proclamation necessary before the constitution was amended to or acts passed to outlaw slavery, it is a de facto violation of states' rights to pass the Controlled Substances Act, at least as it applies to marijuana. These sorts of mistakes are not unheard of, and happen frequently in the budget, as federal and state governments overlap. The only legal option is to encourage or federally mandate amendment of state laws before changing federal law in this matter. In this case, it is clear that the federal government already has a department, the FDA, responsible for this product and stifling research into this promising if dangerous drug is paramount to extortion, incarceration under false pretenses, embezzlement, and treason on a massive scale. Denying this reality and failing to prosecute organizations responsible for the suppression of research and development of this industry as such, would so fundamentally change the mechanisms of this country that entire peoples could be thrown into chains, dispossessed, or in other ways robbed of their fundamental liberties that the government exists to protect under the veil of enhancing freedom and pursuing happiness.

As for constitutionality:
"The embattled Fourth Amendment[117]is probably the leading exam­ple of a “War on Drugs” casualty.[118] As has been erstwhile noted in an apropos reference to George Orwell’s, 1984, a date that we have passed in more than one sense, the “War on Drugs” has led to “[a] gradual but perceptive rise in Big Brotherism against the public at large in the form of eavesdropping, surveillance, monitor­ing, informing, and other intrusive enforcement methods.”[119] Among the inroads that have been sanctioned are those that have permitted intrusions into our homes by the use of aerial surveil­lance,[120] a practice that has led to the practical abandonment in other drug-related contexts of the privacy test announced in Katz v. United States.[121] These relaxations of the restrictions of the Fourth Amendment have allowed the expansion of police authority to carry out warrantless searches for drugs on individuals and automo­biles under circumstances beyond the original intention of Terry’s rationale,[122] which was based on police officer safety, not as a subterfuge, for a search for criminal evidence without meeting the requirements of the Fourth Amendment. The creation of the so-called “good faith” exception to the Fourth Amendment require­ment of probable cause established in United States v. León,[123] which in practice we see stretched beyond “good faith,” is another example of the courts’ permissive attitude towards the government in drug cases. Equally troubling is the upholding of the validity of a warrant issued on the basis of a partially uncorroborated anony­mous tip,[124] leading to cases in which it was allowed to corroborate the anonymous tip by the post facto discovery of illegal evi­dence.[125]"

http://academiajurisprudenciapr.org/new/rethink-the-war-of-drugs/deja-vu-a-federal-judge-revisits-the-war-on-drugs/

PLEASE NOTE: Marijuana was re-legalized in the spending bill of 2014. This was seen as a national security issue and does activate the superiority clause in the Constitution, regardless of state laws. Marijuana is currently legally available for sale and manufacture across the USA on Native American reservations. It is highly probable that state or federal governments will take more responsible steps in the future towards regulating this substance. Also in September leading anti-marijuana academics were caught accepting money from corporate interests, which has changed the field of research in this field significantly.

In regards to state laws and international treaties: Does legal marijuana violate international treaties? The answer is no.
"Even if treaties could override federalism, the agreements that the INCB cites do not purport to do so. The 1961 Single Convention on Narcotic Drugs says compliance is subject to "constitutional limitations" and undertaken with "due regard to [signatories'] constitutional, legal and administrative systems." The 1971 Convention on Psychotropic Substances and the 1988 Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances contain similar provisions."
Representing these treaties in this manner as the INCB has done is criminal, it makes light of legitimate and extremely important resolutions and work the UN has done and made. Now that we can prove that marijuana provides a benefit to public health, we have the right to use and provide it.




"Current marijuana use was significantly correlated (p < 0.05) in a dose- related fashion with a decline in IQ over the ages studied. The comparison of the IQ difference scores showed an average decrease of 4.1 points in current heavy users (p < 0.05) compared to gains in IQ points for light current users (5.8), former users (3.5) and non-users (2.6)."

So use of 5-10 grams (5 joints) of marijuana per week should increase the user's IQ







 Caffeine, recent:


Marijuana can be seen to have in normal doses, less of an effect on the bloodflow of the brain than caffeine.
Cannabis use, long term:













In studies, THC has been found to selectively target cancer cells while leaving healthy ones unharmed.



Most of the problem with marijuana today lies in the fact that it is not regulated. Parasites such as toxoplasmosis gondii end up present in the vast majority of users, and all people with negative side effects from marijuana. A legal industry would clear up the air. Also, unlike alcohol which is associated with a significant drop in national IQ, costing the United States almost 80% of its potential earnings, marijuana and THC is not associated with a decrease in mental functioning for healthy individuals. In Germany, where alcohol consumption dropped by 30% in the last 35 years, marijuana use increased 4 times over from 7% to almost 28% in 18-24 year olds from 1980 to 2015. In the same time period, the economy increased 5 times over from under a trillion dollars GDP to almost the same size as the US economy.

Kraus et al., 2013

Kraus, L., Pabst, A., Piontek, D., and Gomes de Matos, E. Substanzkonsum und substanzbezogene Störungen: Trends in Deutschland 1980–2012 (Substance use and substance use disorders: Trends in Germany 1980–2012) . Substance use and substance use disorders: Trends in Germany 1980–2012Sucht. 2013;59: 333–345



 The IRS is recommending that tax professionals who help state-recognized, legal marijuana businesses "not be considered unethical."



Habit-Forming Substances. The old Act required label disclosure of the quantity or proportion in any drug of twelve listed ingredients or their derivatives.' 99 The list comprised alcohol, several opiates and other narcotic drugs, and acetanilid, a heart depressant used in pain-killers. The Harrison Anti-Narcotic Act in effect supplanted the provision as to most of the listed drugs, but meanwhile public consumption of a number of coal-tar products, more accurately classified as hypnotics than narcotics, had grown to alarming proportions. There is a tendency for the use of these drugs to become habitual, and excessive use produces serious physiological effects. In S. 1944, therefore, the list was broadened, and, to avoid its obsolescence, power was given to the Secretary to add to it.200 Moreover, since the mere statement of the presence of the drug, although of value to the physician, seldom gave warning to the user, a requirement was added that products containing any of the listed ingredients be labeled "Warning-May be Habit-Forming."




Most of these substances include the possibility of an overdose, and so the FDA’s regulations on poison control apply to these substances. This is not the case with marijuana, however, and there are no mortalities associated with the substance. As such, this is a conflict in Federal Statutes which must be resolved in a Federal Court of Law, before prosecution can occur.



Poisonous or toxic materials shall be:

1.     (A) Used according to: 

1.     (1) Law and this Code,

2.     (2) Manufacturer's use directions included in labeling, and, for a pesticide, manufacturer's label instructions that state that use is allowed in a food establishmentP

3.     (3) The conditions of certification, if certification is required, for use of the pest control materials, P and

4.     (4) Additional conditions that may be established by the regulatory authority; and

2.     (B) Applied so that: 

1.     (1) A hazard to employees or other persons is not constituted, P and

2.     (2) Contamination including toxic residues due to drip, drain, fog, splash or spray on foodequipment,utensilslinens, and single-service and single-use articles is prevented, and for a restricted use pesticide, this is achieved by: P 

1.     (a) Removing the items, P

2.     (b) Covering the items with impermeable covers, P or

3.     (c) Taking other appropriate preventive actions, P and

4.     (d) Cleaning and sanitizing equipment and utensils after the application. P

3.     (C) A restricted use pesticide shall be applied only by an applicator certified as defined in 7 USC 136 Definitions, (e) Certified Applicator, of the Federal Insecticide, Fungicide, and Rodenticide Act, or a personunder the direct supervision of a certified applicator. Pf






For these materials used according to Law and this code, includes most drugs, however alcohol marijuana and tobacco cannot be prosecuted under later laws until FDA statutes are amended because they are neither poisonous or toxic, as defined by the US Federal Government. Cannabis is SPECIFICALLY mentioned in this law, and this remains on the books.


  • 4) Notwithstanding paragraph (1)(D) of this subsection, any person who violates subsection (a) of this section by distributing a small amount of marihuana for no remuneration shall be treated as provided in section 844 of this title and section 3607 of title 18.

  • (a) In general
Any individual who knowingly possesses a controlled substance that is listed in section 841(b)(1)(A) of this title in violation of section 844 of this title in an amount that, as specified by regulation of the Attorney General, is a personal use amount shall be liable to the United States for a civil penalty in an amount not to exceed $10,000 for each such violation.”


“Part D — Offenses And Penalties
§844. Penalties for simple possession
(a) Unlawful acts; penalties
It shall be unlawful for any person knowingly or intentionally to possess a controlled substance unless such substance was obtained directly, or pursuant to a valid prescription or order, from a practitioner, while acting in the course of his professional practice, or except as otherwise authorized by this subchapter or subchapter II of this chapter. It shall be unlawful for any person knowingly or intentionally to possess any list I chemical obtained pursuant to or under authority of a registration issued to that person under section 823 of this title or section 958 of this title if that registration has been revoked or suspended, if that registration has expired, or if the registrant has ceased to do business in the manner contemplated by his registration. It shall be unlawful for any person to knowingly or intentionally purchase at retail during a 30 day period more than 9 grams of ephedrine base, pseudoephedrine base, or phenylpropanolamine base in a scheduled listed chemical product, except that, of such 9 grams, not more than 7.5 grams may be imported by means of shipping through any private or commercial carrier or the Postal Service. Any person who violates this subsection may be sentenced to a term of imprisonment of not more than 1 year, and shall be fined a minimum of $1,000, or both, except that if he commits such offense after a prior conviction under this subchapter or subchapter II of this chapter, or a prior conviction for any drug, narcotic, or chemical offense chargeable under the law of any State, has become final, he shall be sentenced to a term of imprisonment for not less than 15 days but not more than 2 years, and shall be fined a minimum of $2,500, except, further, that if he commits such offense after two or more prior convictions under this subchapter or subchapter II of this chapter, or two or more prior convictions for any drug, narcotic, or chemical offense chargeable under the law of any State, or a combination of two or more such offenses have become final, he shall be sentenced to a term of imprisonment for not less than 90 days but not more than 3 years, and shall be fined a minimum of $5,000. Notwithstanding any penalty provided in this subsection, any person convicted under this subsection for the possession of flunitrazepam shall be imprisoned for not more than 3 years, shall be fined as otherwise provided in this section, or both. The imposition or execution of a minimum sentence required to be imposed under this subsection shall not be suspended or deferred. Further, upon conviction, a person who violates this subsection shall be fined the reasonable costs of the investigation and prosecution of the offense, including the costs of prosecution of an offense as defined in sections 1918 and 1920 of title 28, except that this sentence shall not apply and a fine under this section need not be imposed if the court determines under the provision of title 18 that the defendant lacks the ability to pay.”
SUBCHAPTER I — CONTROL AND ENFORCEMENT
Part D — Offenses And Penalties
§844a. Civil penalty for possession of small amounts of certain controlled substances
(a) In general
Any individual who knowingly possesses a controlled substance that is listed in section 841(b)(1)(A) of this title in violation of section 844 of this title in an amount that, as specified by regulation of the Attorney General, is a personal use amount shall be liable to the United States for a civil penalty in an amount not to exceed $10,000 for each such violation.
(b) Income and net assets
The income and net assets of an individual shall not be relevant to the determination whether to assess a civil penalty under this section or to prosecute the individual criminally. However, in determining the amount of a penalty under this section, the income and net assets of an individual shall be considered.
(c) Prior conviction
A civil penalty may not be assessed under this section if the individual previously was convicted of a Federal or State offense relating to a controlled substance.
(d) Limitation on number of assessments
A civil penalty may not be assessed on an individual under this section on more than two separate occasions.
(e) Assessment
A civil penalty under this section may be assessed by the Attorney General only by an order made on the record after opportunity for a hearing in accordance with section 554 of title 5. The Attorney General shall provide written notice to the individual who is the subject of the proposed order informing the individual of the opportunity to receive such a hearing with respect to the proposed order. The hearing may be held only if the individual makes a request for the hearing before the expiration of the 30-day period beginning on the date such notice is issued.
(f) Compromise
The Attorney General may compromise, modify, or remit, with or without conditions, any civil penalty imposed under this section.
(g) Judicial review
If the Attorney General issues an order pursuant to subsection (e) of this section after a hearing described in such subsection, the individual who is the subject of the order may, before the expiration of the 30-day period beginning on the date the order is issued, bring a civil action in the appropriate district court of the United States. In such action, the law and the facts of the violation and the assessment of the civil penalty shall be determined de novo, and shall include the right of a trial by jury, the right to counsel, and the right to confront witnesses. The facts of the violation shall be proved beyond a reasonable doubt.
(h) Civil action
If an individual does not request a hearing pursuant to subsection (e) of this section and the Attorney General issues an order pursuant to such subsection, or if an individual does not under subsection (g) of this section seek judicial review of such an order, the Attorney General may commence a civil action in any appropriate district court of the United States for the purpose of recovering the amount assessed and an amount representing interest at a rate computed in accordance with section 1961 of title 28. Such interest shall accrue from the expiration of the 30-day period described in subsection (g) of this section. In such an action, the decision of the Attorney General to issue the order, and the amount of the penalty assessed by the Attorney General, shall not be subject to review.
(i) Limitation
The Attorney General may not under this subsection \1\ commence proceeding against an individual after the expiration of the 5-year period beginning on the date on which the individual allegedly violated subsection (a) of this section.
---------------------------------------------------------------------------
\1\ So in original. Probably should be "section".
---------------------------------------------------------------------------
(j) Expungement procedures
The Attorney General shall dismiss the proceedings under this section against an individual upon application of such individual at any time after the expiration of 3 years if—
(1) the individual has not previously been assessed a civil penalty under this section;
(2) the individual has paid the assessment;
(3) the individual has complied with any conditions imposed by the Attorney General;
(4) the individual has not been convicted of a Federal or State offense relating to a controlled substance; and
(5) the individual agrees to submit to a drug test, and such test shows the individual to be drug free.

A nonpublic record of a disposition under this subsection shall be retained by the Department of Justice solely for the purpose of determining in any subsequent proceeding whether the person qualified for a civil penalty or expungement under this section. If a record is expunged under this subsection, an individual concerning whom such an expungement has been made shall not be held thereafter under any provision of law to be guilty of perjury, false swearing, or making a false statement by reason of his failure to recite or acknowledge a proceeding under this section or the results thereof in response to an inquiry made of him for any purpose.

THIS MEANS THE Controlled Substances Act is literally screwing over big corporations and the IRS, a fine of $10,000 on 50 kg of marijuana is LESS than taxes in states where marijuana is "legal"
Except where control is required by United States obligations under an international treaty, convention, or protocol, in effect on October 27, 1970, and except in the case of an immediate precursor, a drug or other substance may not be placed in any schedule unless the findings required for such schedule are made with respect to such drug or other substance. The findings required for each of the schedules are as follows:
^^^^ Marijuana has been legal under UN protocols for research purposes, if a student is working with marijuana or any drug for research purposes, they are exempt according to the Controlled Substances Act, this is something that could perhaps be tightened up with academic procedures which in the case of marijuana are not difficult to acquire (previously necessitating a flight to Morocco or an "Indian" reservation, now only to Colorado or Washington, and a growing number of states), but currently this is status quo.


Tuesday, September 23, 2014

Letter from a Birmingham Jail and the Birmingham Campaign


Paul Fischer
9/2014
Dr. Felicia Kornbluh
US History: the 60's

"I am in Birmingham because injustice is here."
Martin Luther King Jr. in Birmingham expanded the movement or Birmingham Campaign beyond the stuffy intellectual laws, decrying the "analysis" that had ineffectively left his people persecuted and poor, while standing up in a tangible and legitimate fashion for what he believed in. Nearly a generation after Gandhi, King shows that unguided protest invites brutality and effectively, if not for his own lifetime then for posterity, provides the case and leadership to fight back against the oppression, segregation, and disenfranchisement of African-Americans in the United States at the time.
At the time of the letter, the movement was the victim of a "broken promise" and Martin Luther King Jr. was facing a withdrawal and retreat from Birmingham. A key part, and he was told by supporters to not do this from lack of popular protest, was the involvement of children in his protest. By moving beyond the conventional means of protest including restaurant sit-ins and bus boycotts to involving the children immediately and directly affected by protest or inaction, Martin Luther King Jr. showed the full involvement and mobilization of these communities towards impacting the dire policies in place.
There are four basic steps to nonviolent campaign, which are outlined in the letter from jail. Then proof is provided that this has occurred in the campaign. The irony of Martin Luther King Jr. writing on whether “you are able to endure the ordeal of jail?” while in jail himself is not lost on the rhetorical power, repition and reinforcement make the letter itself, as a description of a campaign, an example of nonviolent maneuvers in a conflict. This is contracted in a sort of give and take contemporary discussion in the letter which takes multiple viewpoints into consideration while retaining the understanding that there is a common goal for those who will read his letter; it is for the doubting Thomases, the fellow supporters, and the soldiers of equality who marched with him themselves.
The intended audience is important as there is nothing in this letter that could infuriurate one of the oppositional persuasion, in fact it might even bring them around. That is a sign of nonviolent demonstration in itself. The mere point that in this campaign, outlined as a battle without violence, in the publicity of this letter the reverend invites his opponents and friends to the drawing board alike and still retains the moral rectitude and personal control to help them see the moral light as well as the opportunity to give his allies the tools to make progress.  The definition of just and unjust proves a pivotal point in this letter as it is explained that “an unjust law is a code that a numerical or power majority group compels a minority group to obey but does not make binding on itself” and in defining the parameters of action, there has been a philosophical or moral boundary that is crossed over which cannot be retreated.
Though there was ultimately a retreat from Birmingham, it was a retreat of victory. The letter was written, four young school girls had been killed in a church bombing and America began to see the power status quo as barbaric and brutal, reactionary in a silently murderous manner. By appealing beyond those at the planning table or drawing board, the most radical of his compatriots, and appealing to the country’s greater fear of communism, this letter may be written from a jail of defeat but it represents the call to action, like the Gettysburg Address for Abraham Lincoln in the Civil War that will give the Civil Rights movement the authority and power to dwarf and vigorously redefine the opposition as well as their own boundaries and goals.
In the end of the letter, a tribute is paid to those who are the most directly and abundantly targeted with this appeal. His fellow demonstrators, the “demo” teams that blew up American politics in the mid 1960’s, ones who may at the time have felt discouraged or afraid. They may have felt that the battle was uphill or steep, but as he quotes, “My feets is tired, but my soul is at rest” which is not a quote from Gollum of Lord of the Rings but an indication of the undying loyalty of those around him, and of the incipient and pervasive damage on the African-American population of under-education, health-care, and lower standards of living. It shows the willingness of his movement to carry out the battle until it is finished, and to do it on the terms which have been shown to work and are outlined by Martin Luther King Jr. in this letter.

Societal impact of currently under-regulated legal substances: Alcohol and Marijuana in comparison to lead

As seen in the Single Photon Emission Computed Tomography scan imaging, the cognitive damage from alcohol is legitimate; there is damage being done to the brain in significant and substantial amounts over any amount of use. In a heavy marijuana user, one region of the brain increased in function and activity, while the rest remained strong. It would appear that humans have become used to a level of alcohol (a naturally fermenting fruit rotting on the tree at late harvest will not have alcohol over .5%). For adults, while the damage is not permanent, it is significant, and by removing the toxins the brain has the capability of returning to normal. See the video below, posted before, to see an example of this.



What is the impact of this? It was in low and moderate marijuana users found to be nearly 5 points on average an increase in IQ (Fried et al.), there have been studies that suggest marijuana has a detrimental effect though this can be attributed to increased levels of toxoplasma gondii as marijuana is grown in greater amounts in home operations and has exposure to cat feces and has only been observed in states with illegal or decriminalized marijuana laws and recent exposure of leading anti-marijuana academics as corrupt and accepting corporate bribes without disclosing their anti-marijuana bias (Fang). Of low and moderate alcohol users: a "number of studies have noted a measurable diminution in neuropsychologic parameters in habitual consumers of moderate amounts of ethanol" (Eckardt). Taken into context, the estimated damage of lead poisoning (affecting the majority of Americans before the 90's or so, but today only affecting a minority) is 5-10 points  (Bellinger). Translated, as seen on the graph below, this means that the first toxin a population is exposed to will reduce the number of gifted (IQ of 125+) by 80% while when multiple of these are introduced, the bell curve flattens and the damage from 15 points for example will well within 85% (How Pollutants Affect Brain Development). Due to this nature of the bell curve and the improving environmental standards in the United States, there is now the capability to definitely recommend the regulation of alcoholic drinks and foods to under .5 percent.






It should be noted, however, that this graph is not perfectly accurate, and there is a skew on the graph towards a lower IQ where the population is more gradual, as seen demonstrated in actual IQ data below. This means that the effect that is being observed on the high end of the scale is "mirrored" on those with functional or mental retardation and with some substance there is no noticeable effect, and at some point there is an amount at which the number dramatically increase (closer to 20 or 30 points, perhaps associated with illegal narcotic or prescription drug use). An example of this can be seen by looking at the Chinese economy following the legalization of hard drugs in the 1800's which was associated with a loss of approximately 95% of the economy (Major Economies' Share of Global GDP, 0-2005) in just a few generations.
The economic impact of the loss of the gifted group is real, as IQ is directly correlated with achievement, productivity, and income. While the income difference between 90 and 110 IQ points is in the thousands or tens of thousands of dollars, from 110 to 125 or 130 can be over 500,000 dollars annually (seen below, extrapolating decile into percentile using an exponential scale). So it may only be two percent of the population that is substantially impacted by lead poisoning or unregulated alcohol and marijuana, but the impact to the economy is exponentially greater. This can be seen in the change in the workplace today, populations with clean environments, high-tech industry and low substance use rates have averages of 10 or 20, sometimes just 5 or 6 employees for each manager. Low tech industry in the 1960's involved hundreds of employees per manager or executive in companies and poorly qualified supervision. In countries and parts of the US with low environmental standards or high use rates this can continue to be seen, both legally and in illegal sweatshops.

Source: NLSY79, Bureau of Labor Statistics
By regulating the use of these substances to fall within safe levels, the cultural and societal benefits can be retained, while creating an artificial "Flynn" effect, where environmental factors such as health care, nutrition, or mating and marriage regulation and rules gives a boost to the population as seen below.


Addendum: Due to information on infection from toxoplasma gondii and resulting psychosis and schizophrenia that has only been compiled in a meta-analysis in 2014, the impact of marijuana on the IQ may be incorrect in places with legalized marijuana industries. It would appear that the most severe perceived negative effects of marijuana are in actuality the effect of a small parasite that is present in many cats, the fece of which will infect soil and crops in a home-grow operation for up to a year. The information provided here on the impact of illegal or decriminalized marijuana holds, however, as these laws encourage home grown operations meaning many users will contract the parasite as they will buy from a cat owner at some point. In addition the research was confounded using economic variables, and funding was sourced illegitimately to corporations in an investigation.


Bibliography:

Bellinger, David C., Karen M. Stiles, and Herbert L. Needleman. "Low-level lead exposure, intelligence and academic achievement: a long-term follow-up study." Pediatrics 90.6 (1992): 855-861.

Eckardt, Michael J., et al. "Effects of Moderate Alcohol Consumption on the Central Nervous System*." Alcoholism: Clinical and Experimental Research22.5 (1998): 998-1040.


Fried, Peter, et al. "Current and former marijuana use: preliminary findings of a longitudinal study of effects on IQ in young adults." Canadian Medical Association Journal 166.7 (2002): 887-891.

Fang, Lee. "Leading Anti-Marijuana Academics Are Paid By Painkiller Drug Companies | VICE News." VICE News RSS. VICE News, 7 Sept. 2014. Web. 20 Dec. 2014.



Saturday, July 12, 2014

Effects of under-regulated or decriminalized regular or light marijuana and light alcohol use on the brain - Single Photon Emission Computed Tomography


These are the brains of various substance users, alcohol is seen to be incredibly damaging even in weekend only drinking, while marijuana use has an effect observed similar to caffeine. On the right are alcoholic and various other drug users. Using four times a week over the period of three years, this heavy drinker's brain is scalloped out, and damage to the blood circulation in the brain is apparent. In a normal person without any substance use and in continued sobriety, seen at the beginning, there is no damage to the circulation of the brain. Due to statistics suggesting infection from toxoplasmosis, the information provided here regarding marijuana, which is frequently homegrown may be incorrect, however it does show that marijuana use is equivocal to the effect of caffeine with responsible adult use. For those who experience more negative results with marijuana, potential toxoplasmosis gondii infection and hard substance use should be investigated (as both are linked and causal factors in schizophrenia and other disorder cases) and childhood history should be gathered and confirmed using a blood test for the stress hormone cortisol as well, as elevated cortisol levels have been identified as a primary causal factor in adult psychotic depression, and in childhood trauma victims, will be permanently higher (Belanoff). The scan remains an excellent example of light alcohol use as well as the impact of potential parasitic infection from using marijuana in a decriminalized or illegal setting. [Article from News Illustrated, 2013]


With the alcohol and other drug users, this looks like swiss or cottage cheese after decades or years of abuse. Interestingly and significantly, an example of a weekend only drinker is provided. The brain still looks completely decimated by the alcohol use, dismissing the concept that just sometimes using alcohol limits or reduces the damage done by the neuro-toxins present in alcoholic beverages. I wondered what might occur with light marijuana use (and much less alcohol use).
After about a year of sobriety (enough time for the circulation of the brain to return completely to normal), this experiment involved use of one half to one full ounce of marijuana and around 36 beers over a 6 month period and getting a single photon emission computed tomography scan which accurately shows brain function and substance use.


© MCT
Source: The Hanley Center, Amen Clinic, Siemens


First, it is necessary to look at a brain with bad habits and excessive caffeine use, this is a baseline:
                                                                     Daniel's Scan


Marijuana and alcohol use:

Over a six month period, occasional use of around 36 beers, seen following, moderate non-consecutive use and between one half and one full ounce of marijuana, medium quality consumed less than one half of a gram at a time. The damage to blood flow in the brain is clearly beginning in the same areas as that exhibited by an alcohol and marijuana user, though only a fraction of the levels as displayed through heavy use, and consistent with caffeine use. This indicates positively that light substance use has a legitimate and severe negative impact on multiple areas of cognitive and motor skill functioning as well as emotional processing, but is not nearly to the same level as some research has claimed. It must be noted, however, that in a legal setting the impact of pesticide and parasite free marijuana may be completely different from alcohol, and some studies have connected current light marijuana use, that is responsible adult use (5-10 grams per week in Fried et al.) with an increase in IQ (though alcohol remains negative regardless of legality). The scalloping seen on the top of the head is light, and most likely caused by alcohol consumption, along with reduced circulation to decision making and memory functions which are likely caused and exacerbated by marijuana consumption as well, though retrospective research using MRIs suggests that marijuana use may actually increase connectivity and alleviate these symptoms. There is currently no permanent structural damage, as expected as well. No significant history of physical brain trauma, ie. head injury or medical problems to rule out. Some prior use of hallucinogens including absinthe, but several years past and not apparent in this scan. It can also be mentioned before the experiment light alcohol use for 3.5 years and marijuana use for 5 years. The subject was 22 years old, and the brain seen is nearly complete in development, giving an accurate view of the substances involved.

Addendum: Retrospective research by several universities has found that the effects of marijuana on brain structure are such that responsible adult use increases functional connectivity in a dose dependent fashion, though this is only confirmed currently in IQ studies with responsible adult use of marijuana (Filbey). This may be due to different associations with light or heavy marijuana use and nonstandard quality, as noted in the study, "Long-term effects of marijuana use on the brain".

Second Addendum: Results may not be reproducible as lead contamination in marijuana has been confirmed in both Germany and the Northeast of the USA, both of which are regions in which the subject consumed marijuana under decriminalization procedures, a practice carried out by dealers of the historical artifacts to increase profits and potency. A similar research experiment in these regions recorded blood lead levels of around 3.5 micrograms per deciliter one month after cessation and urine THC levels were over 500 ng/mL (or over 10 times the level recorded in a chronic user 12 hours after use), suggesting the high core temperature of a lead-infused joint (1200 degrees centigrade vs. 700 in a cigarette or 500 in pipe tobacco) resulted in significantly more THC absorption than was previously believed. This is confirmed from studies on tobacco which show the absorbed nicotine from cigarettes is 5X greater than that of pipe tobacco, though research on THC absorption as a result of different incineration temperatures is not yet available. Finally, a case-study from Romania has recently shown that the short-term effects of THC are also positive, increasing alertness and even overwhelming the effect of "significant" alcohol intake, which decreased alertness until administration of THC brought the subjects to a level of cognitive functioning even above a control baseline level.

Imaging by Eclipse Nuclear Medicine
Facility: The Hanley Center

Affiliations: Undergraduate research completed while enrolled at the University of Vermont, no declared affiliations.


Bibliography:

Amen, Daniel G., and Martin Waugh. "High resolution brain SPECT imaging of marijuana smokers with AD/HD." Journal of psychoactive drugs 30.2 (1998): 209-214.

Belanoff, Joseph K., et al. "Cortisol activity and cognitive changes in psychotic major depression." (2014).

Callender, Thomas James, Lisa Morrow, and Kodanallur Subramanian. "Evaluation of chronic neurological sequelae after acute pesticide exposure using SPECT brain scans." Journal of Toxicology and Environmental Health, Part A Current Issues 41.3 (1994): 275-284.

Filbey, Francesca M., et al. "Long-term effects of marijuana use on the brain." Proceedings of the National Academy of Sciences 111.47 (2014): 16913-16918.

Fried, Peter et al. “Current and Former Marijuana Use: Preliminary Findings of a Longitudinal Study of Effects on IQ in Young Adults.” CMAJ: Canadian Medical Association Journal 166.7 (2002): 887–891.

Mariani, Giuliano, et al. "A review on the clinical uses of SPECT/CT." European journal of nuclear medicine and molecular imaging 37.10 (2010): 1959-1985.

Torrey, E. Fuller, John J. Bartko, and Robert H. Yolken. "Toxoplasma gondii and other risk factors for schizophrenia: an update." Schizophrenia bulletin 38.3 (2012): 642-647.



Friday, November 22, 2013

NASA Gamma Ray Burst Notes 11.22.2013


Gamma Ray burst
first in six
observed from underground observatory
DRV130427A
Dying star in distant galaxy
one o the brightest we have ever seen
never before seen details challenge our theoretical understanding of how gamma ray bursts work

Charles Dalmer
Astrophysicist in DC, Naval research Laboratory
High energy radiation outbursts

Tom Vestrand
LANL

watches night sky for extra terrestrial objects and things that go bump in the night

Rob Triess
University of Alabama astrophysics
GBM triggered on event on april 27
Interesting behaviour on the first burst of the pulse

Jean-pieroo natafili
Italian Astrophysicist
Gamma ray bursts on laser
new development of telescopes

Sylvia Zoo
Astrophysicist, Maryland
Grad Student
High energy emission from Gamma Ray Bursts
Space craft was able to look at the burst as well as the lab

3 Nasa spacecraft observed gamma ray burst

A Gamma Ray Burst: trans insomething burst of gamma ray radiation from some object in space. after decades of research we find that those gamma rays come from birth of black hole in most cases, this was just an imitation, but only through the development of neew ways of looking to reorient space craft very quickly to get a look at these bursts…

Potential damage of a GRB?
Depends on distance, and if it was pointed at earth (unlikely). atmosphere will generally absorb gamma rays, billions of lightyears away normally. if there was a burst in your galaxy, strong possibility of electronic pulses and ionizing radiation, after time the ozone layer would be destroyed, allowing more radiation and nitrogens would be released, leading to a nuclear winter

why is it important to study GRB?
good question but rhetorical. What was the purpose of uranium study in the early 1900's what was the significance of studying sun burning in the 60's? We do not think this will change the world, but this is an explosion and explosion studies have intrinsic value in field of particle beams and uses to give us greater appreciation of all that occurs in nature.

Tremendous amount of energy in GRB, where does it come from?
Ill pipe up and say in large part we do not really know. The bright part of 13027A is that we can study the bright parts in detail, made possible by Dr. Goerner and ensure that everything goes according to the radiation. We know that energy is directed very efficiently, and seems to convert energy into radiation naturally. Our attempts to do so have fallen flat.

What do scientist learn from studying this?
We were able to identify the first and by doing this we could find a good position and recht we immediately too that these objects were intergalactic and we understood these were very powerful objects, which is useful. There is the object in the radio, 98 percent of the weere Dja gamma ray bursts, it is the most effective way the band to tell theposition and the other band that peopled can follow with instrumentation.

People relate this amount of energy to an atomic bomb. How many atomic bombs would this be equivalent to?
wikipedia says that the most powerful hydrogen bombs released about 15 megatons of TNT equivalent energy. You would need 10^30 of these bombs to have one of these bursts. 

Are these directed in one direction or omnidirectional?
Highly directional. In this particular case, the relatively narrow beam would have to be pointed directly at us.

OK How did one of these spacecraft target this area dn saw the burst before during and after?
The difference between monocular and technicolor. Multiple observations give you so much more information. The earth was not blocked on 1427A so there was allowed onboard triggering and response to move the spacecraft to view the burst. No imaging to know the counterpart without detailed X-rays and other information

More than the electromagnetic spectrum, we are in the EM channels but as time goes on they behave in different manners. Intimate clothing makes another separate high energy radiation situation. Multiple complicated wavelengths

Can one of these occur in our galaxy?
one ever 100 million or 500 million years. these numbers are not certain, but it is something we can expect.

How frequent are these observed?
We have a good idea from orbiting observatory which except for earth blockage we saw the entire sky with gamma rays neural the entire universe with bursts. One per day per universe. So the universe provides that, but we do not know where or when.

How can these bursts affect us if they happen here?
They can if they are in the Milky Way, and one is not really expected here. Might change the atmosphere, perhaps if close by some minor changes could be expected.

Any plans for gamma ray burst science that is coming up?
We are in kind of a climate where we do not anticipate high energy astrophysics new projects. we have two good observatories in orbit andwe have a good life expectancy. The Chinese are planning a follow up in Guam.

If there is an agreement this would happen 1015 2016 probably

Is there a program in place to find or predict the next event?
Lots of attempts ot find a demonstration, we have been able to identify certain stars that are likely to have such an event in their area. Typically at such large distances we cannot see individual stars. Liklihood of such a program being approved is not very likely.

Antimatter?
Model of matter-anti matter shows there is a sizzling layer between the two so there is not lots of emissions except for comets which do not work, i was playing with that.

Locations?
we have plotted them out and they are isotropic. so that is the challenge of building observatories that can observe these at anytime anywhere. no sweet spot to look at.

When one of these assets is in the GRB, what is implicated?
notices are sent out to subscribing astronomers with the BAT instrument and each is hooked into the service and sends information out to interested astronomers. Remote telescopes pick up these messages from the internet real time and reposition to view what is occurring. One of the interesting observational challenges is looking at the gamma ray burst before the explosion occurred. This happened before the event development through the act.

How often can we expect to see a GRB of this size?
Typical of gamma, what is unusual is how near by this  burst was. Every 60 years or so we can infer this sort of event happens once or twice very unique every century.

Whatis interesting here/?
persistent afterglow (optical) we knew about this but this one is beautifully interesting because there is such persistence of high energy gamma rays. This persistent gamma ray is caused by some shock etc…

how does this GRB compare to photo extinction event?
first one has to convince people studying that a major extinction event was causedby GRB, personally thinks it is due to volcanic activity. within the milky way it would have to oerate.

one thing that is sot interesting is that the cataclysmic event happened over an extended period. but the gamma ray burst would be  a one - two punch. so the cosmic rays can cause global cooling. There are some behavioural extinction that occurs within those patterns. The patterns in the galaxy are so rare and unlikely, we like to think this is not the case despite tantalizing suggestion.

how big can a gamma ray burst get? upper levels?
The seem to originate in massive stars. All the energy that is equivalent to the rest mass of the sun is equivalent to the mass of the sun. these are isotropic events that are equivalent to outflows and jets, the upper limit is determined by the size of the star that is the preginature of the burst.

How does the GRB actually start?
the most energetic GRB: not proven that black holes are the power, could also be certain stars, for example evidence in plateaus from swift telescope. In many occasions this is pullover. can be monitored in terms of absolute energy. Directed into a very small jet we get very small bursts. We have to figure out what we see versus what really is. This is a difficult or tricky situation to evaluate.
How do they Start!
There is a massive star with fuel and that fuel is spent, put under neutrons degeneracy pressure, yields a black hole, natural situation. 

Is the Gamma Ray Radiation so to speak a beam like a laser?
No and no.

Is there enough energy that it fuses the heaviest elements?
Conference in Kudo where modelling of fusing into higher atomic mass elements was assimilated and it seems to a pretty good approximation gives the highest level elements, so the possibility is yes we can produce some fraction of the heavy metals involved. Excellent question because it ties to how these are related. there would not be a supernova formation event. people look at gamma ray events where black hole is forming massive satr.

Why is there a difference?
The optical light is generated often by lower energy particles and maybe accelerated in different ways. From optical illusion, we think they are generated by exactly the same process. With this other type of optical illusion which we see it is kind of the glowing embers of the explosion, if you will. But not at these lower energy gamma ray emissions, we will often see after these GRE.

Terrestrial GRB?
terrestrial gamma ray flashes are by fermee no way to object the fields of electrons over electric storms. and we see energies high enough to produce pares of electrons and positrons. also quite interesting but a completely different phenomenon

What do X-rays bring to the table in GRB study?
We see some evolution occurring. It sees then that whitefish the spectrum doesn ot change over housr minutes and days. it is some level of information from before. even there we thought the spectrum was exactly the same up to 73. but this was also interpretation as well compared to modern interpretation.

anything else?
it was interesting in the lab because it gave us pop to study something far away and normally something this close is weak, but this was more of an ordinary monster, but close to earth. previously we had a model that explains the HEE very well. We did not see things before when the bursts were very close to us. For these events we required that we think back or tweak our models or something. Also because it was so close we had to observe for 20 hours, something with HEGR.

We saw this on 4/27 but how long did it take for that energy to get to us? when was it born?
black hole was born about 3.75 billion years ago, so this was a young burst all the same, because many we see are 5 or 10 billion years old. Because it is young the signal is very strong. when the earth was then, it looked very different and the whole universe looked different.

The important question is how to measure distance and that is astronomy?
Chuck was lost.

Could the GRB signal an extinction event on mars? such as disappearance of an atmosphere?
No, it is very different, off the road ap, very unlikely. 

Can we assume the burst occurs as a creation event of every black hole?
it is very likely that these happen when a very massive star, the core of one into another. highly magnetized neutron star. so not entirely accurate to say each of these has a black hole, and also not true that all black holes come from this.

What is the effect of gravity on this explosion?
detailed modelling of the collapse of a massive star into nothing, yields a lot of damage giving characteristic signature on gamma ray waves. should be simultaneous, and gravity wave radiations.

Vapor with the optical data, if this interpretation is correct we look at less than 3 million degrees. but his is not cut, there is a discussion about it. a few degrees.

Has this burst actually changed any of our understanding about how stars evolve?
no, because apart from the energy emission it is very similar to the other GRB, what is actually this burst, we can see the Supernova, usually associated to very long bursts, much weaker. This is not very far away, and we can see the entirety of the burst, usually one or two up to 6 or 7 or 9 we have seen so far, something supernova.

Friday, November 8, 2013

Notes for Calculus 1 - CYR


Chart is key to doing this type of problem
f'(x)=4x^3-48x=0
4x(x^2-12)=0
x=0 or x^2-12=0
=>x^2=12
x=2+-(v--3)
f''(x)=12x^2-48=0
12(x^2-4)=0
12(x+2)(x-2)=0
x=+-2
-4 -3 -1 1 3     4
    (-@@,-2V--3)|(-2V--3,-2)|(-2,0)|(0,2)|(2,2V--3)|(2V--3,@@)
f'(x)+-     |(-) (+)     (+)     (-)       (-)     (+)
f''(x)+-     |   (+)                       (+)     (-)       (-)       (+)            (+)
inc/dec     | dec inc     inc     inc    dec       inc
concave up/down|up up     down down up     up
sketch     |          U intersect(grk) U
noticing mirror like combinations of positive to negative values, whengl
f'(x)=4x^3-48x
=4x(x^2-12)
f'(-4)=4(-4)((-4)^2-12) will be negative
f'(-3)=4(-3)((-3)^2-12)positive
f'(-1)=4(-1)((-1)^2-12)positive
extrapolated application of number to variables

rel max @ (0,f(0))
rel. min.@ (2V--3, f(2V--3)) and -2V--3, f(-2V--3)) (2root3, -66) and (-2root3, -66)
f(x)=x^4-24x^2+80
f(0)=80
f(2V--3)=16*9-24(4*3)+80
146-288+80=0
=-146+80= -66
^^same as f(-2V--3)


Exam Prep
Relative Extreme
very similar to what we get on the test, parts a  thru e
just fill in all the blanks
not too hard, just to remember what is going on
any specific questions or walkthrough?
some derivatives?
probably one that involves more than one rule
List out all the rules-2columns
1) first side:
Derivatives we know
f(x)=x^n
=polynomial
e^x or a^x
ln^x
sinx cosx
2) rules to use we can "break up functions"
product rule u(x)-v(x)
quotient rule: p(x)/q(x)
chain rule: u(v(x))

ex) f(x) = sin^2(x+1/x)
=(sin(x+1)/(x))^2
CHAIN RULE
u(x)=x^2
u'(x)=2x
v(x)=sin((x+1)/x)
chain rule again
g(x)=sinx
g'(x)=cosx
h(x)=(x+1)/x
h(x)=(x/x)+1/x)
h'(x)=x^-2
v'(x)=g'(h(x))*h'(x)
=cos((x+1)/x)(-x^-2)
=-cos((x+1)/x)/x^2
f'(x)=u'(v(x))*v'(x)
2(sin((x+1)/x)(-cos((x+1)/x)^2)
ex) f(x)=(x^2-2)/e^x^2
Quotient rule: 
p(x)=x^2-2
p'(x)=2x
q(x)=e^x^2
CHAIN RULE: q=u(v(x))
u(x)=e^x
u'(x)=e^x)
v(x)=x^2
v'(x)=2x
q'(x)=e^x*(2x)
f'=(e^x^2*2x-(x^2-2)(2xe^x^2))/(e^x^2)^2
=(2xe^x^2)-(2x^3e^x^2)+(4xe^x^2)/(e^2x^2)
=(xe^x^2)(6-2x^2)/(e^x^2)^2
=x(6-2x^2)/(e^x^2)

f(x)=3xe^x+2
find where ifs inc/dec,
concave up/down
PRODUCT RULE
u(x)=3x 
u'(x)=3
v(x)=e^x
v'(x)=e^x
f'(x)=3e^x+3xe^x
3e^x+3xe^x=0<- to find CNS
3e^x(1+x)=0 e^ ANYTHING IS NEVER ZERO
1+x=0
x=-1 CN
f'(-2)=3e^-2(1-2)
f'(0)=3e^0(1-0) --> Positive!

f is increasing on interval (-1,@@)
and decreasing on (-@@,-1)
would increase product rule but we are smart and we realize hey, this is the derivative of 3xe^x
f''(x)=3e^x+(3e^x+3xe^x)
6e^x+3xe^x
3e^x(2+x)=0
x=-2
f''(-3)=3e^-3(2-3) gives NEGATIVE
f''(0)=3e^0(2-0)>0
f is concave up on (-2,@@)
down on (-@@,-2)
only way we know when it goes up to down is at inflection points

149 at drug test lab ate one pack of old (hard) swedish fish
ray expected to call in 45 minutes or an hour
ray never calls, tells me to fuck off when I call him> NO DRUG TEST TAKEN
Must find rent.